2023年7月27日发(作者：)

Material Safety Data SheetIssuing Date

07/14/09Revision Number

01. PRODUCT AND COMPANY IDENTIFICATIONProduct NameProduct Code(s)DistributorAMRESCO INC.6681 Cochran RoadSOLON, OHIO 44139Company Phone NumberEmergency Telephone Number1-800-829-2805Chemtrec 1-800-424-9300Amphotericin B, SolubilizedE4372. HAZARDS IDENTIFICATIONEmergency OverviewIrritantSensitizerAppearance

Light yellowPotential Health EffectsAcute ToxicityEyesSkinInhalationIngestionChronic EffectsAggravated Medical ConditionsEnvironmental HazardPhysical State

Powder, LyophilizedOdor

No information availableIrritating to ting to skin. May cause sensitization by skin ting to respiratory system. May cause sensitization by irritation by known effect based on information Section 12 for additional Ecological Information.3. COMPOSITION/INFORMATION ON INGREDIENTSChemical NameAmphotericin BCAS-No1397-89-3Weight %0-24. FIRST AID MEASURESEye ContactSkin ContactInhalationRinse thoroughly with plenty of water for at least 15 minutes and consult a skin with soap and to fresh air. If breathing becomes difficult, give oxygen._____________________________________________________________________________________________Page 1 / 5Revision DateProduct Code(s)MSDS E437

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Amphotericin B, Solubilized_____________________________________________________________________________________________IngestionNotes to PhysicianClean mouth with water and afterwards drink plenty of symptomatically.5. FIRE-FIGHTING MEASURESFlammable PropertiesFlash PointSuitable Extinguishing MediaHazardous Combustion ProductsExplosion DataSensitivity to Mechanical ImpactSensitivity to Static DischargeProtective Equipment and Precautions for FirefightersNot determinedDry chemical, CO2, water spray or regular oxides, Nitrogen oxides (NOx)Not in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and fullprotective ity

-Physical and ChemicalHazards

-NFPAHealth Hazard

-Flammability

-6. ACCIDENTAL RELEASE MEASURESPersonal PrecautionsAvoid contact with skin, eyes and clothing. Use personal protective equipment. Ensureadequate t further leakage or spillage if safe to do dust formation. Pick up and transfer to properly labeled containers. Ventilate areaand wash spill site after material pickup is s for ContainmentMethods for Cleaning Up7. HANDLING AND STORAGEHandlingLight Sensitive. Moisture sensitive. Handle in accordance with good industrial hygiene andsafety t from light. Protect from moisture. Keep containers tightly closed in a dry, cool andwell-ventilated e8. EXPOSURE CONTROLS / PERSONAL PROTECTIONChemical NameAmphotericin B 1397-89-3ACGIH TLVOSHA PELNIOSH IDLHEngineering MeasuresShowersEyewash stationsVentilation al Protective EquipmentEye/Face ProtectionAvoid contact with eyes. Safety glasses with side-shields._____________________________________________________________________________________________Page 2 / 5Revision DateProduct Code(s)MSDS E437

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Amphotericin B, Solubilized_____________________________________________________________________________________________Skin and Body ProtectionRespiratory ProtectionWear protective gloves/ exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approvedrespiratory protection should be worn. Positive-pressure supplied air respirators may berequired for high airborne contaminant concentrations. Respiratory protection must beprovided in accordance with current local in accordance with good industrial hygiene and safety e Measures9. PHYSICAL AND CHEMICAL PROPERTIESAppearancePhysical StateFlash PointBoiling Point/RangeExplosion LimitsSolubilityVapor DensityLight yellowPowder, LyophilizedNo information availableNo information availableNo information availableNo information availableNo information ation RateNo information availableOdorAutoignition TemperatureFlammability Limits in AirNo information availableNo information availableNo information available10. STABILITY AND REACTIVITYStabilityIncompatible ProductsConditions to AvoidStable under recommended storage known based on information t from light. Protect from ous Decomposition ProductsCarbon oxides. Nitrogen oxides (NOx).Hazardous PolymerizationHazardous polymerization does not occur.11. TOXICOLOGICAL INFORMATIONAcute ToxicityProduct InformationCauses skin, eye and respiratory tract irritation. al NameAmphotericin BLD50 Oral5 g/kg ( Rat )LD50 DermalLC50 InhalationChronic ToxicityTarget Organ EffectsKidney12. ECOLOGICAL INFORMATIONEcotoxicityThe environmental impact of this product has not been fully investigated._____________________________________________________________________________________________Page 3 / 5Revision DateProduct Code(s)MSDS E437

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Amphotericin B, Solubilized_____________________________________________________________________________________________13. DISPOSAL CONSIDERATIONSWaste Disposal MethodDispose of material in accordance with all federal, state, and local inated PackagingChemical NameAmphotericin B - 1397-89-3Chemical NameAmphotericin B - 1397-89-3Dispose of in accordance with all federal, state and local - HalogenatedOrganic CompoundsRCRA - P Series WastesRCRA - F Series WastesRCRA - K Series Wastes14. TRANSPORT INFORMATIONDOTIATAIMDG/IMONot regulatedNot regulatedNot regulated15. REGULATORY INFORMATIONInternational InventoriesTSCADSLEINECS/ELINCSENCSIECSCKECLPICCSAICSDoes not ComplyDoes not ComplyCompliesDoes not ComplyDoes not ComplyDoes not ComplyCompliesCompliesU.S. Federal RegulationsSARA 313Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product contains a chemicalor chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372:SARA 311/312 Hazard CategoriesAcute Health HazardChronic Health HazardFire HazardSudden Release of Pressure HazardReactive HazardYesNoNoNoNoClean Water ActThis product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40CFR 122.42)._____________________________________________________________________________________________Page 4 / 5Revision DateProduct Code(s)MSDS E437

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Amphotericin B, Solubilized_____________________________________________________________________________________________Clean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61)This product does not contain any substances regulated as hazardous air pollutants (HAPS) under Section 112 of the Clean Air ActAmendments of U.S. State RegulationsCalifornia Proposition 65This product does not contain any Proposition 65 ational RegulationsMexico - GradeNo information This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) andthe MSDS contains all the information required by the Hazard ClassNot determined16. OTHER INFORMATIONIssuing DateRevision DateRevision NoteNo information available.07/14/09DisclaimerThe information provided on this MSDS is correct to the best of our knowledge, information and belief at the date of itspublication. The information given is designed only as a guide for safe handling, use, processing, storage,transportation, disposal and release and is not to be considered as a warranty or quality specification. The informationrelates only to the specific material designated and may not be valid for such material used in combination with any othermaterial or in any process, unless specified in the of MSDS_____________________________________________________________________________________________Page 5 / 5