2024年4月11日发(作者：)

美国药典（USP）中规定的色谱柱类型

Chromatographic Reagents

The following list of packings (L), phases (G), and supports (S) is intended to be

a convenient reference for the chromatographer. [note—Particle sizes given in this

listing are those generally provided. Where other, usually finer, sizes are required,

the individual monograph specifies the desired particle size. Within any category

of packings or phases listed below, there may be a wide range of columns available.

Where it is necessary to define more specifically the chromatographic conditions,

the individual monograph so indicates.]

Change to read:

Packings

L1—Octadecyl silane chemically bonded to porous silica or ceramic

micro-particles, 1.5 to 10 µm in diameter, or a monolithic silica rod.

L2—Octadecyl silane chemically bonded to silica gel of a controlled surface

porosity that has been bonded to a solid spherical core, 30 to 50 µm in

diameter.

L3—Porous silica particles, 3

USP31

to 10 µm in diameter, or a

monolithic silica rod.

USP31

L4—Silica gel of controlled surface porosity bonded to a solid spherical core,

30 to 50 µm in diameter.

L5—Alumina of controlled surface porosity bonded to a solid spherical core,

30 to 50 µm in diameter.

L6—Strong cation-exchange packing–sulfonated fluorocarbon polymer

coated on a solid spherical core, 30 to 50 µm in diameter.

L7—Octylsilane chemically bonded to totally porous silica particles, 1.5 to 10

µm in diameter, or a monolithic silica rod.

USP31

L8—An essentially monomolecular layer of aminopropylsilane chemically

bonded to totally porous silica gel support, 3 to 10 µm in diameter.

L9—Irregular or spherical, totally porous silica gel having a chemically bonded,

strongly acidic cation-exchange coating, 3 to 10 µm in diameter.

L10—Nitrile groups chemically bonded to porous silica particles, 3 to 10

µm in diameter.

L11—Phenyl groups chemically bonded to porous silica particles, 1.5 to 10

µm in diameter.

L12—A strong anion-exchange packing made by chemically bonding a

quaternary amine to a solid silica spherical core, 30 to 50 µm in diameter.